| Date | Opponent | Location | Playoffs |
|---|---|---|---|
| 8/27/2021 | Appleton City | Appleton City | |
| 9/3/2021 | Albany* | Stanberry | |
| 9/10/2021 | King City* | King City | |
| 9/24/2021 | Pattonsburg* | Pattonsburg | |
| 10/1/2021 | North Andrew* | Stanberry | |
| 10/8/2021 | North Shelby | Stanberry | |
| 10/15/2021 | East Atchison | East Atchison | |
| 10/22/2021 | Worth County* | Worth County | |
| 11/5/2021 | South Holt | South Holt | Districts |
| 11/12/2021 | Worth County | Worth County | Districts |