| Date | Opponent | Location | Tournament |
|---|---|---|---|
| 3/22/2021 | DeKalb | South Harrison | |
| 3/23/2021 | North Harrison | South Harrison | |
| 3/25/2021 | Southwest Livingston | Southwest Livingston | |
| 3/29/2021 | North Andrew | North Andrew | |
| 3/30/2021 | Maryville | South Harrison | |
| 4/1/2021 | Putnam County* | South Harrison | |
| 4/3/2021 | Babe Adams Baseball Tournament | South Harrison | Babe Adams |
| 4/8/2021 | Milan* | South Harrison | |
| 4/12/2021 | Albany | Albany | |
| 4/15/2021 | Maysville* | Maysville | |
| 4/22/2021 | Princeton* | South Harrison | |
| 4/23/2021 | Stewartsville-Osborn | Stewartsville-Osborn | |
| 4/26/2021 | Pattonsburg | Pattonsburg | |
| 4/27/2021 | Cameron | South Harrison | |
| 4/29/2021 | Trenton* | Trenton | |
| 5/3/2021 | King City | South Harrison | |
| 5/6/2021 | GRC West | South Harrison | |
| 5/10/2021 | Braymer | South Harrison |