| Date | Opponent | W/L | Score | Opp Score | Location | Playoffs |
|---|---|---|---|---|---|---|
| 8/27/2021 | North Shelby | L | 0 | 22 | Maysville | |
| 9/3/2021 | North Platte | W | 28 | 8 | North Platte | |
| 9/10/2021 | Polo* | L | 11 | 17 | Maysville | |
| 9/17/2021 | South Harrison* | L | 0 | 14 | South Harrison | |
| 9/24/2021 | Gallatin* | L | 20 | 26 | Maysville | |
| 10/1/2021 | Princeton* | W | 45 | 22 | Princeton | |
| 10/8/2021 | Trenton* | L | 8 | 34 | Trenton | |
| 10/15/2021 | Putnam County* | W | 51 | 8 | Maysville | |
| 10/22/2021 | Milan* | L | 12 | 28 | Milan | |
| 10/29/2021 | Milan | L | 6 | 20 | Milan | Districts |